靶标：
Ifitm5
产品别名：
1110003J06Rik； AW213665； Bril； DSPA1； Hrmp1； Hrtm1； Ifitm5； interferon induced transmembrane protein 5； interferon induced transmembrane protein 5； interferon-induced transmembrane protein 5； bone-restricted interferon induced transmembrane protein-like protein； dispanin subfamily A member 1； fragilis family member 4； haemopoiesis related membrane protein 1； 干扰素诱导跨膜蛋白5；
背景信息：
IFITM5 is a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).
