靶标:
Igfbpl1
产品别名:
2810011G06Rik; 2810453O06Rik; IGFBPL; Igfbpl1; insulin-like growth factor binding protein-like 1; insulin-like growth factor binding protein-like 1; insulin-like growth factor-binding protein-like 1; IGFBP-like protein; IGFBP-rP4; IGFBP-related protein 10; insulin-like growth factor-binding-related protein 4; 胰岛素样生长因子结合蛋白样1;
背景信息:
function:IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.,induction:Down-regulated in multiple tumors.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 Kazal-like domain.,tissue specificity:Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.,