靶标:
Cep112
产品别名:
1700001M19Rik; 1700029K01Rik; 8430407H02Rik; AV043680; AV207351; Ccdc46; Macoco; Cep112; centrosomal protein 112; centrosomal protein 112; centrosomal protein of 112 kDa; coiled-coil domain containing 46; coiled-coil domain-containing protein 46; 卷曲螺旋结构域蛋白46;
背景信息:
This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],