靶标:
Upp2
产品别名:
1700124F02Rik; AI266885; UDRPASE2; UP2; UPASE2; Upp2; uridine phosphorylase 2; uridine phosphorylase 2; uridine phosphorylase 2; L-UrdPase; liver-specific uridine phosphorylase; 尿嘧啶核苷磷酸化酶2(UPP2);
背景信息:
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.