靶标:
Sla2
产品别名:
A930009E21Rik; AI430952; SLAP-2; SLAP2; Sla2; Src-like-adaptor 2; Src-like-adaptor 2; src-like-adapter 2; modulator of antigen receptor signaling MARS; src-like adapter protein 2;
背景信息:
This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.