靶标:
PTGES2
产品别名:
C9orf15; GBF-1; GBF1; PGES2; mPGES-2; PTGES2; prostaglandin E synthase 2; prostaglandin E synthase 2; prostaglandin E synthase 2; GATE-binding factor 1; gamma-interferon-activated transcriptional element-binding factor 1; mPGE synthase-2; membrane-associated prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; prostaglandin-H(2) E-isomerase; 前列腺素E合成酶2; 前列腺素E合酶2(PTGES2);
背景信息:
Microsomal prostaglandin E synthase-2 (mPGES-2) or Prostaglandin E synthase 2 is an enzyme that in humans encoded by the PTGES2 gene located on chromosome 9. The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.