靶标:
ZFP91
产品别名:
DMS-8; DSM-8; DSM8; FKSG11; PZF; ZFP-91; ZNF757; ZFP91; ZFP91 zinc finger protein, atypical E3 ubiquitin ligase; ZFP91 zinc finger protein, atypical E3 ubiquitin ligase; E3 ubiquitin-protein ligase ZFP91; RING-type E3 ubiquitin transferase ZFP91; drug resistance-associated sequence in melanoma 8; penta zinc finger protein; zinc finger protein 757; zinc finger protein 91 homolog; zinc finger protein homologous to Zfp91 in mouse; 白血病相关新基因;
背景信息:
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010],