靶标:
KCNH6
产品别名:
ERG-2; ERG2; HERG2; Kv11.2; hERG-2; KCNH6; potassium voltage-gated channel subfamily H member 6; potassium voltage-gated channel subfamily H member 6; potassium voltage-gated channel subfamily H member 6; eag-related gene member 2; ether-a-go-go-related protein 2; potassium channel, voltage gated eag related subfamily H, member 6; potassium voltage-gated channel, subfamily H (eag-related), member 6; voltage-gated potassium channel subunit Kv11.2; KCNH6蛋白;
背景信息:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013],