靶标:
TRIM8
产品别名:
FSGSNEDS; GERP; RNF27; TRIM8; tripartite motif containing 8; tripartite motif containing 8; E3 ubiquitin-protein ligase TRIM8; RING-type E3 ubiquitin transferase TRIM8; glioblastoma-expressed RING finger protein; probable E3 ubiquitin-protein ligase TRIM8; ring finger protein 27; tripartite motif protein TRIM8; 环指蛋白27; 胶质母细胞瘤表达环指蛋白(GERP);
背景信息:
This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE).