靶标:
FCRL4
产品别名:
CD307d; FCRH4; IGFP2; IRTA1; FCRL4; Fc receptor like 4; Fc receptor like 4; Fc receptor-like protein 4; IFGP family protein 2; fc receptor homolog 4; fcR-like protein 4; hIFGP2; immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; CD307d蛋白;
背景信息:
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009],