靶标:
L3MBTL2
产品别名:
H-l(3)mbt-l; L3MBT; L3MBTL2; L3MBTL histone methyl-lysine binding protein 2; L3MBTL histone methyl-lysine binding protein 2; lethal(3)malignant brain tumor-like protein 2; H-l(3)mbt-like protein 2; L(3)mbt-like protein 2; L3MBTL2, polycomb repressive complex 1 subunit; l(3)mbt-like 2; 致死因子恶性脑瘤样蛋白2;
背景信息:
Putative Polycomb group (PcG protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.