靶标:
STARD13
产品别名:
ARHGAP37; DLC2; GT650; LINC00464; STARD13; StAR related lipid transfer domain containing 13; StAR related lipid transfer domain containing 13; stAR-related lipid transfer protein 13; Rho GTPase activating protein on chromosome 13q12; StAR-related lipid transfer (START) domain containing 13; deleted in liver cancer 2 protein; long intergenic non-protein coding RNA 464; 肝癌缺失基因2;
背景信息:
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],