靶标:
MYLK3
产品别名:
MLCK; MLCK2; caMLCK; MYLK3; myosin light chain kinase 3; myosin light chain kinase 3; myosin light chain kinase 3; MLC kinase; cardiac-MLCK; cardiac-MyBP-C associated Ca/CaM kinase; putative myosin light chain kinase 3; 肌球蛋白轻链激酶3; 肌球蛋白轻链激酶3(MYLK3);
背景信息:
YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.