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C型凝集素结构域家族6成员A抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Anti-CLEC6A
Anti-C-type lectin domain containing 6A Antibody
靶标:

CLEC6A


产品别名:

CLEC4N; CLECSF10; dectin-2; hDECTIN-2; CLEC6A; C-type lectin domain containing 6A; C-type lectin domain containing 6A; C-type lectin domain family 6 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10; C-type lectin superfamily member 10; DC-associated C-type lectin 2; dectin 2; dendritic cell-associated C-type lectin 2; C型凝集素结构域家族6成员A;


背景信息:
The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
 
 
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