靶标：
Nlrp6
产品别名：
AI504961； Avr； Nalp6； Navr； Navr/Avr； Non-AVR； Pypaf5； Nlrp6； NLR family, pyrin domain containing 6； NLR family, pyrin domain containing 6； NACHT, LRR and PYD domains-containing protein 6； NACHT, leucine rich repeat and PYD containing 6； NACHT/LRR/pyrin domain-containing protein 6； PYRIN-containing APAF1-like protein 5； angiotensin II/vasopressin receptor； non-angiotensin-vasopressin receptor； 富含亮氨酸重复结构域蛋白6；
背景信息：
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
