靶标:
Cmtm7
产品别名:
AI481279; Cklfsf7; LNV; Cmtm7; CKLF-like MARVEL transmembrane domain containing 7; CKLF-like MARVEL transmembrane domain containing 7; CKLF-like MARVEL transmembrane domain-containing protein 7; chemokine-like factor super family 7; chemokine-like factor superfamily member 7; 趋化素样因子超家族成员7;
背景信息:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],