靶标:
Nudt19
产品别名:
D7Rp2; D7Rp2-r; D7Rp2-s; D7Rp2e; RP2-r; RP2-s; Nudt19; nudix (nucleoside diphosphate linked moiety X)-type motif 19; nudix (nucleoside diphosphate linked moiety X)-type motif 19; acyl-coenzyme A diphosphatase NUDT19; RP2p; androgen regulated gene RP2; androgen-regulated protein RP2; nucleoside diphosphate-linked moiety X motif 19, mitochondrial; nudix motif 19; renal CoA diphosphohydrolase; testosterone-regulated RP2 protein; NUDT19蛋白;
背景信息:
NUDT19 (nudix (nucleoside diphosphate linked moiety X)-type motif 19), also known as RP2, is a 375 amino acid protein and coenzyme A diphosphatase that assists in the hydrolysis of CoA esters. A member of the nudix hydrolase family, NUDT19 contains one nudix hydrolase domain and localizes to both mitochondria and peroxisome. NUDT19 utilizes magnesium and/or manganese as cofactors and is encoded by a gene that maps to human chromosome 19q13.11. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.