靶标:
IL22RA2
产品别名:
CRF2-10; CRF2-S1; CRF2X; IL-22BP; IL-22R-alpha-2; IL-22RA2; ZCYTOR16; IL22RA2; interleukin 22 receptor subunit alpha 2; interleukin 22 receptor subunit alpha 2; interleukin-22 receptor subunit alpha-2; cytokine receptor class-II member 10; cytokine receptor family type 2, soluble 1; interleukin 22 receptor, alpha 2; interleukin 22-binding protein; 白介素22受体α2(IL22Ra2); 白介素22受体结合蛋白;
背景信息:
This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013],