靶标:
ZFYVE27
产品别名:
PROTRUDIN; SPG33; ZFYVE27; zinc finger FYVE-type containing 27; zinc finger FYVE-type containing 27; protrudin; spastic paraplegia 33 protein; zinc finger FYVE domain containing 27; 锌指FYVE结构域蛋白27;
背景信息:
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010],