靶标：
JAML
产品别名：
AMICA； AMICA1； CREA7-1； CREA7-4； Gm638； JAML； junction adhesion molecule like； junction adhesion molecule like； junctional adhesion molecule-like； adhesion molecule AMICA； adhesion molecule interacting with CXADR antigen 1； adhesion molecule, interacts with CXADR antigen 1； dendritic-cell specific protein CREA7-1； dendritic-cell specific protein CREA7-4； 粘附分子JAML蛋白；
背景信息：
domain:The Ig-like V-type domain 2 mediates interaction with CXADR.,function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,
