靶标:
UPRT
产品别名:
FUR1; UPP; UPRT; uracil phosphoribosyltransferase homolog; uracil phosphoribosyltransferase homolog; uracil phosphoribosyltransferase homolog; RP11-311P8.3; UMP pyrophosphorylase; UPRTase; uracil phosphoribosyltransferase (FUR1) homolog; 尿嘧啶磷酸核糖转移酶(UPRT);
背景信息:
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]