靶标：
Rspo1
产品别名：
R-spondin； Rspondin； Rspo1； R-spondin 1； R-spondin 1； R-spondin-1； R-spondin homolog； cristin-3； cysteine-rich and single thrombospondin domain-containing protein 3； mCristin-3； roof plate-specific spondin-1； thrombospondin type 1 domain containing gene Rspondin； R-脊椎蛋白1(RSPO1)； 分泌性蛋白RSPO1；
背景信息：
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
