靶标：
NLRP7
产品别名：
CLR19.4； HYDM； NALP7； NOD12； PAN7； PYPAF3； NLRP7； NLR family pyrin domain containing 7； NLR family pyrin domain containing 7； NACHT, LRR and PYD domains-containing protein 7； NACHT, LRR and PYD containing protein 7； NACHT, leucine rich repeat and PYD containing 7； PYRIN-containing Apaf1-like protein 3； nucleotide-binding oligomerization domain protein 12； nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7； 富含亮氨酸重复结构域蛋白7；
背景信息：
NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
