靶标:
Ankk1
产品别名:
9930020N01Rik; Ankk1; ankyrin repeat and kinase domain containing 1; ankyrin repeat and kinase domain containing 1; ankyrin repeat and protein kinase domain-containing protein 1; 锚定蛋白重复结构域蛋白激酶ANKK1;
背景信息:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],