靶标:
IFNL2
产品别名:
IFNL2a; IFNL3a; IL-28A; IL28A; IFNL2; interferon lambda 2; interferon lambda 2; interferon lambda-2; IFN-lambda-2; cytokine Zcyto20; interleukin 28A (interferon, lambda 2); interleukin-28A; 白介素28A(IL28A); 白细胞介素28A;
背景信息:
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008],