靶标:
FAT2
产品别名:
CDHF8; CDHR9; HFAT2; MEGF1; SCA45; FAT2; FAT atypical cadherin 2; FAT atypical cadherin 2; protocadherin Fat 2; FAT tumor suppressor homolog 2; cadherin family member 8; cadherin-related family member 9; multiple EGF-like domains protein 1; multiple epidermal growth factor-like domains 1; multiple epidermal growth factor-like domains protein 1; protocadherin FAT2;
背景信息:
This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008],