靶标:
SKIC2
产品别名:
170A; DDX13; HLP; SKI2; SKI2W; SKIV2; SKIV2L; SKIV2L1; THES2; SKIC2; SKI2 subunit of superkiller complex; SKI2 subunit of superkiller complex; helicase SKI2W; SKI2 homolog, superkiller viralicidic activity 2-like; Ski2 like RNA helicase; helicase-like protein; superkiller viralicidic activity 2-like;
背景信息:
DEAD box proteins, characterized byThe conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases.They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based onTheir distribution patterns, some members ofThis family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs.This gene is located inThe class III region ofThe major histocompatibility complex. [provided by RefSeq, Jul 2008]