靶标:
SPINK2
产品别名:
HUSI-II; SPGF29; SPINK2; serine peptidase inhibitor Kazal type 2; serine peptidase inhibitor Kazal type 2; serine protease inhibitor Kazal-type 2; epididymis tissue protein Li 172; serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor); 丝氨酸蛋白酶抑制剂SPINK2;
背景信息:
SPINK2 Antibody: Human serine proteinase inhibitor Kazal-type 2 (SPINK2) is required for maintaining normal spermatogenesis and potentially regulates serine protease-mediated apoptosis in male germ cells. It contains a typical kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. SPINK2 plays a role in the pathogenesis of hereditary and chronic pancreatitis.