靶标：
SLC7A6
产品别名：
LAT-2； LAT3； y+LAT-2； SLC7A6； solute carrier family 7 member 6； solute carrier family 7 member 6； Y+L amino acid transporter 2； amino acid permease； cationic amino acid transporter, y+ system； solute carrier family 7 (amino acid transporter light chain, y+L system), member 6； solute carrier family 7 (cationic amino acid transporter, y+ system), member 6； y(+)L-type amino acid transporter 2； y+LAT2；
背景信息：
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
