靶标:
HS3ST3A1
产品别名:
3-OST-3A; 3OST3A1; HS3ST3A1; heparan sulfate-glucosamine 3-sulfotransferase 3A1; heparan sulfate-glucosamine 3-sulfotransferase 3A1; heparan sulfate glucosamine 3-O-sulfotransferase 3A1; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; heparan sulfate 3-O-sulfotransferase 3A1; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; heparin-glucosamine 3-O-sulfotransferase; HS3ST3A1蛋白;
背景信息:
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.