靶标:
DOP1B
产品别名:
21orf5; C21orf5; DOPEY2; DOP1B; DOP1 leucine zipper like protein B; DOP1 leucine zipper like protein B; protein dopey-2; dopey family member 2; homolog of yeast DOP1; 迟钝蛋白家族2;
背景信息:
Dopey-2, a 2,298 amino acid protein, belongs to the dopey family, that is overexpressed in lymphoblasts from Down syndrome patients and Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon. Multiple isoforms of Dopey-2 exist due to alternative splicing events. Dopey-2 is thought to play a role in protein trafficking between early endosomes and the late.