靶标：
H13
产品别名：
1200006O09Rik； 4930443L17Rik； 5031424B04Rik； AV020344； H-13； Hm13； PSL3； Spp； H13； histocompatibility 13； histocompatibility 13； minor histocompatibility antigen H13； presenilin-like aspartyl protease； presenilin-like protein 3； signal peptide peptidase beta；
背景信息：
H13 catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. It is required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. Involved in the intramembrane cleavage of the integral membrane protein PSEN1 By similarity. It may play a role in graft rejection.
