靶标:
Klra6
产品别名:
Ly49f; ly-49f; Klra6; killer cell lectin-like receptor, subfamily A, member 6; killer cell lectin-like receptor, subfamily A, member 6; killer cell lectin-like receptor 6; T-cell surface glycoprotein Ly-49F; lymphocyte antigen 49f;
背景信息:
Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.