靶标：
DENND3
产品别名：
DENND3； DENN domain containing 3； DENN domain containing 3； DENN domain-containing protein 3； DENN/MADD domain containing 3； DENND3蛋白；
背景信息：
DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
