位置:首页 > 产品库 > CAMSAP2抗体
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CAMSAP2抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Anti-CAMSAP2
Anti-calmodulin regulated spectrin associated protein family member 2 Antibody
靶标:

CAMSAP2


产品别名:

CAMSAP1L1; CAMSAP2; calmodulin regulated spectrin associated protein family member 2; calmodulin regulated spectrin associated protein family member 2; calmodulin-regulated spectrin-associated protein 2; calmodulin-regulated spectrin-associated protein 1-like protein 1;


背景信息:
Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytoskeleton, also regulates the organization of cellular organelles including the Golgi and the early endosomes. Essential for the tethering, but not for nucleation of non-centrosomal microtubules at the Golgi: together with Golgi-associated proteins AKAP9 and PDE4DIP, required to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Also acts as a regulator of neuronal polarity and development: localizes to non-centrosomal microtubule minus-ends in neurons and stabilizes non-centrosomal microtubules, which is required for neuronal polarity, axon specification and dendritic branch formation. Through the microtubule cytoskeleton, regulates the autophagosome transport.
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2025