靶标:
DNAJC13
产品别名:
PARK21; RME8; DNAJC13; DnaJ heat shock protein family (Hsp40) member C13; DnaJ heat shock protein family (Hsp40) member C13; dnaJ homolog subfamily C member 13; DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; required for receptor-mediated endocytosis 8; DNAJC13蛋白;
背景信息:
This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016],