靶标:
KCNH4
产品别名:
BEC2; ELK1; Kv12.3; KCNH4; potassium voltage-gated channel subfamily H member 4; potassium voltage-gated channel subfamily H member 4; potassium voltage-gated channel subfamily H member 4; ELK channel 1; brain-specific eag-like channel 2; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 1; potassium channel, voltage gated eag related subfamily H, member 4; potassium voltage-gated channel, subfamily H (eag-related), member 4; voltage-gated potassium channel subunit Kv12.3; KCNH4蛋白;
背景信息:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008],