靶标:
Ifi202b
产品别名:
Ifbip-1; Ifi202; Ifi202a; Ifi202c; p202; Ifi202b; interferon activated gene 202B; interferon activated gene 202B; interferon-activable protein 202; Interferon-activatable protein 202a (Ifi-202a) (Interferon-inducible protein p202a); ifi-202; interferon activated gene 202A; interferon-inducible protein p202; lupus susceptibility protein p202; γ干扰素诱导蛋白202;
背景信息:
Interferon-activable protein 202 (Ifi202b, p202) belongs to the HIN-200 family and contains two HIN-200 domains. It is reported to inhibit transcriptional activity of several transcription factors, including NF-kappaB p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. It has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. It is an interferon-inducible protein which is responsible for Lupus susceptibility and is induced by Interleukin-6.