靶标:
CPAMD8
产品别名:
ASGD8; K-CAP; VIP; CPAMD8; C3 and PZP like alpha-2-macroglobulin domain containing 8; C3 and PZP like alpha-2-macroglobulin domain containing 8; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; alpha-2 macroglobulin family protein VIP; CPAMD8蛋白;
背景信息:
CPAMD8 belongs to the complement component-3 (C3; 120700)/alpha-2-macroglobulin (A2M; 103950) family of proteins, which are involved in innate immunity and damage control. The encoded protein is membrane-associated and proteolytically processed to generate two chains. Mutations in this gene cause a form of anterior segment dysgenesis, a developmental disorder of the eye. By genomic sequence analysis, the CPAMD8 gene is mapped to chromosome 19p13.3-p13.2.