靶标:
tsr
产品别名:
12/8; ADF; ADF/cofilin; Adf; CG4254; Cadf; D-cof; D61; Dmel\CG4254; T8; Tsr; cofilin; cofilin/ADF; cofilin/actin depolymerizing factor homolog; l(2)03101; l(2)k03101; l(2)k05633; l(2)k13409; ntf; tsr; twinstar; twinstar; twinstar; ADFcofilin; CG4254-PA; Cofilin/actin depolymerizing factor-like; DCofilin; actin-depolymerizing factor; cofilin; no terminal filament; tsr-PA; twin star;
背景信息:
Exhibits F-actin depolymerizing activity and regulates actin cytoskeleton dynamics (PubMed:21205790). Required for cytokinesis in both mitotic and meiotic cells and for aster migration and separation (PubMed:8522587). Promotes cell motility during ovary development and oogenesis (PubMed:11175754). During larval development, required for the cell rearrangement needed for formation of terminal filaments which are stacks of somatic cells that are important for the initiation of ovarioles (PubMed:11175754).