Anti-Atp8a2
Anti-ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 Antibody
靶标:
Atp8a2
产品别名:
AI415030; Atpc1b; agil; wl; Atp8a2; ATPase, aminophospholipid transporter-like, class I, type 8A, member 2; ATPase, aminophospholipid transporter-like, class I, type 8A, member 2; phospholipid-transporting ATPase IB; ATPase 8A2, class I; ATPase 8A2, p type; ATPase class I type 8A member 2; ATPase, class 1, member a; P4-ATPase flippase complex alpha subunit ATP8A2; probable phospholipid-transporting ATPase IB;
背景信息:
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes, the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth. Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Required for normal visual and auditory function; involved in photoreceptor and inner ear spiral ganglion cell survival.
宿主:Rbt
类型:Pab
同种型:IgG
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。