靶标:
UNC93A
产品别名:
Unc-93A; dJ366N23.1; dJ366N23.2; UNC93A; unc-93 homolog A; unc-93 homolog A; protein unc-93 homolog A; dJ366N23.1 (putative C. elegans UNC-93 (protein 1, C46F11.1) LIKE); dJ366N23.2 (putative C. elegans UNC-93 (protein 1, C46F11.1) C-terminal LIKE); unc93 homolog A;
背景信息:
Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.