靶标:
PLEKHA5
产品别名:
PEPP-2; PEPP2; PLEKHA5; pleckstrin homology domain containing A5; pleckstrin homology domain containing A5; pleckstrin homology domain-containing family A member 5; PH domain-containing family A member 5; phosphoinositol 3-phosphate-binding protein-2; pleckstrin homology domain containing, family A member 5; 磷酸肌醇3磷酸结合蛋白2;
背景信息:
Pleckstrin homology domain-containing family A member 5 is a protein that in humans is encoded by the PLEKHA5 gene. This gene, which encodes a transcriptional repressor, is one of two paralogous X-linked homeobox-containing genes and is highly expressed in a variety of cancers. In addition, the encoded protein associates with the cell membrane and with microtubules and is concentrated at the leading edge of migratory cells.