靶标:
WBP1L
产品别名:
C10orf26; OPA1L; OPAL1; WBP1L; WW domain binding protein 1 like; WW domain binding protein 1 like; WW domain binding protein 1-like; outcome predictor in acute leukemia 1; OPA1L蛋白;
背景信息:
OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.