靶标：
ATP13A1
产品别名：
ATP13A； CGI-152； ATP13A1； ATPase 13A1； ATPase 13A1； endoplasmic reticulum transmembrane helix translocase； ATPase type 13A1； cation transporting ATPase； endoplasmic reticulum P5A-ATPase； manganese-transporting ATPase 13A1； probable cation-transporting ATPase 13A1；
背景信息：
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.
