靶标:
ARHGAP23
产品别名:
ARHGAP23; Rho GTPase activating protein 23; Rho GTPase activating protein 23; rho GTPase-activating protein 23; rho-type GTPase-activating protein 23;
背景信息:
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008],