靶标：
PLEKHG2
产品别名：
ARHGEF42； CLG； CTB-60E11.4； LDAMD； PLEKHG2； pleckstrin homology and RhoGEF domain containing G2； pleckstrin homology and RhoGEF domain containing G2； pleckstrin homology domain-containing family G member 2； PH domain-containing family G member 2； common-site lymphoma/leukemia guanine nucleotide exchange factor； pleckstrin homology domain containing, family G (with RhoGef domain) member 2； 含普列克底物蛋白家族G成员2；
背景信息：
PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
