靶标:
Tsen34
产品别名:
0610027F08Rik; Leng5; Tsen34; tRNA splicing endonuclease subunit 34; tRNA splicing endonuclease subunit 34; tRNA-splicing endonuclease subunit Sen34; leukocyte receptor cluster (LRC) member 5; leukocyte receptor cluster member 5 homolog; tRNA splicing endonuclease 34 homolog; tRNA-intron endonuclease Sen34;
背景信息:
This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]