靶标:
Glipr1l2
产品别名:
4921508O11Rik; Glipr1l2; GLI pathogenesis-related 1 like 2; GLI pathogenesis-related 1 like 2; GLIPR1-like protein 2; 胶质瘤发病相关蛋白1样蛋白2;
背景信息:
The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (2). GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma (4).