靶标:
Lrrc34
产品别名:
1700007J06Rik; SPATA34; Lrrc34; leucine rich repeat containing 34; leucine rich repeat containing 34; leucine-rich repeat-containing protein 34; spermatogenesis associated SPATA34; 富含亮氨酸重复蛋白34;
背景信息:
Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro.